New molecular targets (ARF GTPases) can improve early diagnosis of prostate cancer and prediction of its progression

Prostate cancer (PCa) is the most common cancer in men (excluding non melanoma skin cancer) in the UK with over 40,000 cases diagnosed each year (CancerResearchUK [2015]). However, for some men with early stage PCa that is confined to the prostate the disease may never be life threatening and can follow and indolent course which…

Diabetes drug targeting glucose transport may impact treatment of prostate cancer and highlights potential importance of PET imaging

UCLA scientists have identified a new mechanism that delivers a key substance that fuels the growth of pancreatic and prostate cancer cells, a finding that offers new hope in the fight against two of the deadliest forms of the disease. Cancer cells require high amounts of the sugar glucose to survive and grow, and long-standing…

US Senator Nelson (D-FLA) , aged 72, announced that routine prostate cancer screening enabled early diagnosis and successful treatment.

Democratic Sen. Bill Nelson of Florida will undergo prostate cancer surgery at a local hospital Monday, his office said Thursday. Doctors found the cancer during a routine exam, according to a release from his office. It said Nelson had no symptoms and “extensive” scans showed no evidence the cancer has spread outside the prostate. Nelson,…

Researchers discovered a molecule (DNA-PKcs) promoting prostate cancer metastases and opening new pathways for drug development and testing

For the first time, a single molecule has been identified that could be central to the mechanism of spread by prostate cancer. The findings could lead to a new prostate cancer drug target. The study is published in the journal Cancer Cell and was completed by researchers from the Thomas Jefferson University in Philadelphia, PA.…

New York Times: Bring PSA Screening Back

FOR years, research on prostate cancer has sought an approach to screening that is more individualized than a one-size-fits-all measurement of the level of prostate-specific antigen in a man’s blood. These efforts are now paying off. That’s why it’s time to re-evaluate the nation’s current approach to prostate cancer. Even though we anticipate 221,000 new…

NCCN Guidelines for Prostate Cancer Screening 2015 Endorse PSA and its Advanced Versions

The 2015 update of the guidelines for prostate cancer from the National Comprehensive Cancer Network (NCCN) marks the 20th annual edition of the guidance. The update contains three major changes, which are related to imaging, molecular testing, and the systemic treatment of castration-resistant disease, said James Mohler, MD, who chairs the NCCN panel for prostate…