Virtual | September 22-24, 2022
THURSDAY, SEPTEMBER 22, 2022
8:00 AM – 9:45 AM
SESSION I: PATIENT POPULATION PRIOR TO DIAGNOSIS OF PROSTATE CANCER: SCREENING AND CLINICAL EVALUATION OF MEN WITH CLINICAL SUSPICION
State of the Art in Prostate Cancer Screening
Current and Emerging Diagnostic Tools for Improving Risk Assessment, Selection of Patients for Biopsy and Tissue Sampling
10:15 AM – 12:00 PM
Current and Emerging Diagnostic Tools for Improving Risk Assessment, Selection of Patients for Biopsy and Tissue Sampling (Continued)
NCCN Guidelines for Early Detection of Prostate Cancer 2021
Integrated Multi-Modality Diagnostic Evaluation
12:00 PM – 2:00 PM
LUNCH BREAK
2:00 PM – 3:30 PM
SESSION II. CLINICAL EVALUATION AND MANAGEMENT OF MEN WITH LOCALIZED AND RECURRENT PROSTATE CANCER
Liquid Markers
Tissue-Based Genetic Cancer Profiling
Pathology
4:00 PM – 5:30 PM
SESSION II. CLINICAL EVALUATION AND MANAGEMENT OF MEN WITH LOCALIZED AND RECURRENT PROSTATE CANCER
In Vivo Imaging
FRIDAY, SEPTEMBER 23, 2022
8:00 AM – 9:25 AM
SESSION II: CLINICAL EVALUATION AND MANAGEMENT OF MEN WITH LOCALIZED AND RECURRENT PROSTATE CANCER (Continued)
In Vivo Imaging (continued)
10:00 AM – 11:10 AM
Integration of Precision Diagnosis and Precision Treatment
11:10 AM – 1:30 PM
LUNCH BREAK
1:30 PM – 3:00 PM
SESSION III: POPULATION OF MEN WITH ADVANCED PROSTATE CANCER
Treatment for Advanced Prostate Cancer, including Oligometastatic and Systemic Disease
3:30 PM – 5:30 PM
Molecular and Multi-Modality Imaging and Theranostics
SATURDAY, SEPTEMBER 24, 2022
8:00 AM – 10:30 AM
SESSION IV: PRECISION DIAGNOSTICS AND EMERGING ROLE OF IMAGE-TARGETED, MINIMALLY INVASIVE TREATMENT
Multimodality Diagnostics for Improved Target Definition, Patient Selection, Monitoring & Outcomes
10:30 AM – 1:00 PM
LUNCH BREAK
1:00 PM – 1:45 PM
PANEL ON PRECISION CARE AND HEALTH DISPARITIES IN PROSTATE CANCER
1:45 PM – 3:20 PM
PANEL ON BIOINFORMATICS, ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING FOR A MULTIMODALITY DATA ANALYSIS FOR PRECISION DIAGNOSIS AND TREATMENT
3:20 PM – 3:40 PM:
PRESENTATION OF WINNING ABSTRACTS
3:40 PM – 5:30 PM
SUMMARY PANEL DISCUSSION – SUMMIT HIGHLIGHTS
5:30 ADJOURN
8:15 am SESSION I: PATIENT POPULATION PRIOR TO DIAGNOSIS OF PROSTATE CANCER: SCREENING AND CLINICAL EVALUATION OF MEN WITH CLINICAL SUSPICION
Moderators:
Jim C. Hu, MD, MPH, Ronald P. Lynch Professor of Urologic Oncology and Professor of Urology, Weill Cornell Medical College, Cornell University; and Attending Urologist, New York-Presbyterian Hospital
Laurence Klotz, MD, Professor of Surgery, University of Toronto and Chair of Prostate Cancer Research, Sunnybrook Medical Center, University of Toronto, Canada; and Chair, World Urologic Oncology Federation
Grannum Sant, MD, FRCS, FACS, Professor and Former Chair of Urology, Tufts University School of Medicine; Former Head, Oncology/Urology Medical Affairs, Sanofi, and Rare Genetic Diseases, Genzyme
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Clare M. C. Tempany-Afdhal, MB BAO BCh, FACR, FISMRM, Ferenc Jolesz MD Professor of Radiology Harvard Medical School; Vice-Chair, Radiology Research Brigham & Women’s Hospital; Director of the Ferenc Jolesz National Center for Image-Guided Therapy & AMIGO; and Chair, Joint American College of Radiology, AdMeTech Foundation and European Society of Urogenital Radiology Steering Committee on PI-RADS Standardization (TBC)
8:30 am Topic 1: State of the Art in Prostate Cancer Screening
Sigrid Carlsson, MD, PHD, MPH, Assistant Attending Epidemiologist, Departments of Surgery (Urology Service) and Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center and Associate Professor of Experimental Urology, Sahlgrenska Academy, Gothenburg University, Sweden
8:42 am Q & A
8:44 am Topic 2: Current and Emerging Diagnostic Tools for Improving Risk Assessment, Selection of Patients for Biopsy and Tissue Sampling
8:44 am Topic 2A: Current and Emerging Liquid Diagnostics
8:44 am Keynote Address – Clinical Perspective on Current and Emerging Liquid Diagnostics
E. David Crawford, MD, Professor of Urology, University of California San Diego; Chairman, Prostate Conditions Education Council; Editor in Chief, Grand Rounds in Urology; and Prostate Cancer Series Editor, Oncology Journal (TBC)
8:56 am Q & A
8:58 am – 9:15 am Panel Discussion – Liquid Biomarkers
Speakers and Mark Katz, MD, Assistant Professor of Surgery, Boston University School of Medicine
9:15 am Topic 2B: The Re-Emergence of Transperineal Prostate Biopsy – Current and Future Clinical Role
Edward Schaeffer, MD, PhD, Edmund Andrews Professor and Chair, Department of Urology, Northwestern University (TBC)
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9:27 am Q & A
9:30 am Topic 2C: Current and Emerging Imaging Tools and Targeted Biopsies
9:30 am Advanced Ultrasound
Ethan Halpern, MD, Professor and Vice Chair for Research; Co-Director, Prostate Diagnostic Center; and Director, Cardiac CT, Thomas Jefferson University
9:42 am Q & A
9:45 am – 10:15 am COFFEE BREAK
10:15 am Multi-Parametric (mp) and Bi-Parametric (bp) Magnetic Resonance Imaging
10:15 am Recent Advancements in PI-RADS Standardization
Clare Tempany, MD
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10:27 am Q & A
10:30 am American College of Radiology Prostate MRI Image Quality Initiative
Jeffrey Weinreb, MD, Professor, Department of Diagnostic Radiology and Biomedical Imaging, Yale School of Medicine and Chief of MRI Services, Yale-New Haven Hospital
.
10:42 am Q & A
10:44 am MRI-targeted Biopsy of the Prostate for Improved Tissue Sampling
.Mukesh Harisinghani, MD, Director of Abdominal MRI, Massachusetts General Hospital and Professor of Radiology, Harvard Medical School
10:56 am Q & A
11:00 am Panel Discussion: Imaging Modalities and Targeted Biopsies
11:30 am Topic 3: NCCN Guidelines for Early Detection of Prostate Cancer 2021
Preston Sprenkle, MD, Assistant Professor of Surgery, Yale University School of Medicine; and Member, NCCN Prostate Cancer Early Detection Panel
11:42 am Q & A
11:44 am Topic 4: Integrated Multi-Modality Diagnostic Evaluation
Robert E. Reiter, MD, MBA, Bing Professor in Prostate Cancer; Director, Prostate Cancer Program and Chief, Division of Urologic Oncology; Assistant Dean, Bioentrepreneurship; Department of Urology, David Geffen School of Medicine at UCLA Institute of Urologic Oncology
11:56 am Q & A
12:00 pm – 2:00 pm LUNCH BREAK
2:00 pm SESSION II: CLINICAL EVALUATION AND MANAGEMENT OF MEN WITH LOCALIZED AND RECURRENT PROSTATE CANCER
Moderators:
Matthew R. Cooperberg, MD, MPH, Professor of Urology and Epidemiology & Biostatistics and Associate Chair for Clinical Research, Department of Urology; Helen Diller Family Chair in Urology, UCSF
.
Masoom Haider, MD, Professor of Radiology, University of Toronto; Senior Clinician Scientist, Lunenfeld Tanenbaum Research Institute; Director, Machine Learning and Radiomics Lab; and Director, Sinai Health System Research MRI, Canada
.
Alan Pollack, MD, PhD, Professor and Chairman of Radiation Oncology, University of Miami Miller School of Medicine; Interim Deputy Director, Sylvester Comprehensive Care Center; and Service Chief, Radiation Oncology, Jackson Memorial Hospital (Invited)
.
2:30 pm Topic 1: Liquid Markers – Proteomics and Germline Genome
Paul Boutros, PhD, MBA, Director of Cancer Data Science, Jonsson Comprehensive Cancer Center; Associate Director of Cancer Informatics at the Institute for Precision Health; and Professor of Urology and Human Genetics, UCLA
2:42 pm Q & A
2:44 pm Topic 2: Overview of Tissue-Based Genetic Cancer Profiling
2:56 pm Q & A
3:00 pm Topic 3: Pathology Overview
Thomas Wheeler, MD, Chief of Pathology and Laboratory Medicine, Baylor St. Luke’s Medical Center, and W. L. Moody, Jr. Endowed Chair, Professor and Senior Vice Chair, Department of Pathology & Immunology, Baylor College of Medicine
.
3:12 pm Q & A
3:15 pm – 3:30 pm Panel Discussion: Liquid Markers and Tissue Sampling and Analysis
3:30 pm – 4:00 pm COFFEE BREAK
4:00 pm Topic 4: In Vivo Imaging
4:14 pm Topic 4B: Molecular Imaging
4:14 pm Overview
Andrei H. Iagaru, MD, FACNM, Professor of Radiology – Nuclear Medicine Chief, Division of Nuclear Medicine and Molecular Imaging Co-Director, PET-MRI Research Program Stanford University
4:26 pm Q & A
4:28 pm Clinical Utility of Axumin
Gerald L. Andriole, MD, Robert Royce Distinguished Professor, Chief of Urologic Surgery, and Vice-Chair, Department of Surgery, Washington University School of Medicine, Barnes-Jewish Hospital, Siteman Cancer Center; and Member, National Comprehensive Cancer Network (NCCN)’s Cancer Early Detection Panel
.
4:40 pm Q & A
4:42 pm – 5:00 pm Panel Discussion: Prostate Imaging
5:00 pm – 5:30 pm GENERAL DISCUSSION
8:00 am SESSION II: CLINICAL EVALUATION AND MANAGEMENT OF MEN WITH LOCALIZED AND RECURRENT PROSTATE CANCER (Continued)
Moderators:
Andrei H. Iagaru, MD, FACNM
Adam Kibel, MD, Elliott Carr Cutler Professor of Surgery, Harvard Medical School; Chief of Urology, Brigham and Women’s Hospital and Dana-Farber Cancer Institute (TBC)
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Kelvin A. Moses, MD, PhD, FACS, Associate Professor of Urology, Urologic Oncology Fellowship Director, and Director of Comprehensive Prostate Cancer Clinic, Vanderbilt University Medical Center, and Chair, NCCN Prostate Cancer Early Detection Guidelines Panel
Lalitha K. Shankar, MD, PhD, Chief, Clinical Trials Branch, Cancer Imaging Program, National Cancer Institute
.
8:30 am Topic 4B: Molecular and Multi-Modality Imaging
8:30 am PSMA Imaging – Emerging Clinical Utility from Radiologic Perspective
Thomas Hope, MD, Associate Professor of Radiology and Director of Molecular Therapy in the Department of Radiology and Biomedical Imaging; Chair of the Cancer Center’s Molecular Imaging & Radionuclide Therapy Site Committee, University of California, San Francisco; Chief of Nuclear Medicine at the San Francisco VA Medical Center
8:42 am Q & A
8:44 am Molecular Imaging – Current and Future Research
Steven Rowe, MD, PhD, Associate Professor of Radiology and Radiologic Science, Johns Hopkins University School of Medicine
8:56 am Q & A
8:58 am – 9:10 am Panel Discussion: Molecular Imaging
9:10 am Topic 5: Urologic Perspective on the Current and Emerging Role of Multi-Modality Imaging and Radiogenomics
Mohummad Minhaj Siddiqui, MD, Associate Professor of Surgery, Director of Urologic Oncology and Robotic Surgery, University of Maryland Medical System, and Chief of Urology, Baltimore VA Medical Center; and Participant, US Vice President Joseph Biden’s Cancer Moonshot Program
9:22 am Q & A
9:25 am – 10:00 am COFFEE BREAK
10:00 am Topic 6: Integration of Precision Diagnosis and Precision Treatment
10:00 am Topic 6A: Integrated Diagnostics (Radiogenomics) and Active Surveillance: Patient and Monitoring
Sanoj Punnen, MD, MAS, Co-Chair of Genitourinary Site Disease Group, Pap Corps Champions for Cancer Research Endowed Chair in Solid Tumor Research and Associate Professor, Department of Urology, University of Miami, Miller School of Medicine
10:12 am Q & A
10:14 am Topic 6B: Selection and Monitoring of Image-Targeted Minimally Invasive Treatment
Fiona Fennessy, MB, Bch, PhD, Associate Professor of Radiology, Harvard Medical School; Faculty Radiologist, Brigham & Women’s Hospital; Program Director, Cancer Imaging Fellowship Program; and Institute Physician, Dana-Farber Cancer Institute
10:26 am Q & A
10:28 am Topic 6C: Overview of Role of Imaging for Precision Radiation Treatment
Ashesh Jani, MD, MSEE, FASTRO, Professor, Department of Radiation Oncology, Emory University
10:40 am Q & A
10:42 am Topic 6D: Overview of Surgical Treatment
Adam Feldman, MD, MPH, Assistant Professor of Surgery, Harvard Medical School; and Director, Combined Harvard Urologic Oncology Fellowship
10:54 am Q & A
10:56 am Topic 6E: NCCN Guidelines for Treatment of Localized Prostate Cancer
Kelvin A. Moses, MD, PhD
11:08 am Q & A
11:10 am – 1:30 pm LUNCH BREAK
1:30 pm SESSION III: POPULATION OF MEN WITH ADVANCED PROSTATE CANCER
Moderators:
Neil H. Bander, MD, Bernard & Josephine Chaus Professor of Urologic Oncology, Weill Cornell Medicine (TBC)
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David Nanus, MD, Mark W. Pasmantier Professor of Hematology and Medical Oncology in Medicine, and Director of the New York-Presbyterian Hospital – Weill Cornell Medicine Healthcare System Cancer Program (TBC)
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Michael Morris, MD, Medical Oncologist, Memorial Sloan Kettering Cancer Center (TBC)
.
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2:00 pm Topic 1: Treatment for Advanced Prostate Cancer, including Oligometastatic and Systemic Disease
2:00 pm Topic 1A: Standard Treatment and Global Prostate Cancer Issues
Marc Garnick, MD, Director of Cancer Community Services, Network Development, BIDMC, Gorman Brothers Clinical Professor of Medicine at Harvard Medical School (HMS), Special Advisor, Oncologic Drugs Advisory Committee of the FDA
.
2:12 pm Q & A
2:14 pm Topic 1B: Epigenetic Modulations and Lineage Plasticity
Himisha Beltran, MD, Associate Professor of Medicine, Harvard Medical School and Director of Translational Research, Department of Medical Oncology, Dana-Farber Cancer Institute
.
2:26 pm Q & A
2:28 pm Topic 1C: Novel Treatment and Its Integration With Precision Diagnostics
2:40 pm Q & A
2:42 pm – 3:00 pm Panel Discussion: Standard and Emerging Treatment
3:00 pm – 3:30 pm COFFEE BREAK
3:30 pm Topic 2: Molecular and Multi-Modality Imaging and Theranostics
3:30 pm Topic 2A: Overview of Non-Invasive and Intraoperative PSMA Imaging
Wolfgang Weber, MD, Professor and Chair, Department of Nuclear Medicine, Klinikum der Isar, Technical University of Munich, Germany
3:42 pm Q & A
3:44 pm Topic 2B: Defining Non-Metastatic and Oligometastatic Prostate Cancer vs. Systemic Disease
Jeremie Calais, MD, MSc, Assistant Professor, Clinical Research Program Director, Nuclear Medicine and Theranostics, University of California, Los Angeles
3:56 pm Topic 2C: Current State of the Art and Future Vision in Theranostics
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Philip Koo, MD, Division Chief, Diagnostic Imaging, Banner MD Anderson Cancer Center
4:08 pm Q & A
4:10 pm – 4:30 pm Discussion of Molecular and Multi-Modality Imaging and Theranostics
4:30 pm – 5:30 pm GENERAL DISCUSSION
8:00 am SESSION IV: PRECISION DIAGNOSTICS AND EMERGING ROLE OF IMAGE-TARGETED, MINIMALLY INVASIVE TREATMENT: Multimodality Diagnostics for Improved Target Definition, Patient Selection, Monitoring & Outcomes
Moderators:
David Albala, MD, Chief of Urology, Crouse Hospital in Syracuse, New York; and Visiting Professor of Urology SUNY Downstate Health Sciences University, College of Medicine
Mitchell Sokoloff, MD, Professor and Chair of Urology, University of Massachusetts School of Medicine
Sadhna Verma, MD, Professor of Radiology, University of Cincinnati College of Medicine
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Stephen Zappala, MD, Clinical Assistant Professor, Department of Urology, Tufts University School of Medicine
.
8:30 am Overview
Jurgen Fütterer, MD, PhD, Interventional Radiologist, Professor of Image-guided Interventional Oncology, Radboud University Medical Center, Nijmegen, and Professor, Robotics and Mechanics Group, University of Twente, The Netherlands
8:42 am Q & A
8:44 am Radiologic Perspective on Patient Selection & Outcomes
John Feller, MD, Chief Medical Officer, HALO Dx; and Assistant Clinical Professor of Radiology, Loma Linda University School of Medicine
8:56 am Q & A
8:58 am Image-Guided Laser Ablation – Experience at the University of Chicago
Aytekin Oto, MD, Professor and Chairman of Radiology, University of Chicago
9:10 am Q & A
9:12 am Follow-Up of Focal Cryoablation and Novel Pulse Sequences to Characterize the Treatment Zone
Daniel Margolis, MD, Associate Professor of Radiology and Director, Prostate MRI and Abdominal Imaging, Weill Cornell Medicine
9:24 am Q & A
9:26 am Image-Guided High Intensity Focal Ultrasound – Recent Clinical Trials
Steven Raman, MD, Clinical Professor of Radiology and Director of Prostate MR Imaging and Interventions, David Geffen School of Medicine, UCLA
9:38 am Q & A
9:40 am Urologic Perspective on Clinical Utility and Outcomes
9:54 am Radiation Oncology Perspective
Daniel Y. Song, MD, Professor of Radiation Oncology and Molecular Radiation Sciences, and Co-Director, Prostate Cancer Multi-Disciplinary Clinic, Johns Hopkins University (TBC)
10:06 am Q & A
10:08 am Panel Discussion: Image-Guided Treatment
10:30 am – 1:00 pm LUNCH BREAK
1:00 pm PANEL ON PRECISION CARE AND HEALTH DISPARITIES IN PROSTATE CANCER
Moderators:
Adam B Murphy, MD, MBA, MSCI, Assistant Professor, Department of Urology & Preventive Medicine, Northwestern Medicine – Feinberg School of Medicine, Affiliate Member of Institute for Global Health and Center for Community Health (TBC)
Quoc-Dien Trinh, MD, Co-Director, Dana-Farber/Brigham and Women’s Prostate Cancer Program; Director, Ambulatory Clinical Operations, Division of Urological Surgery; and Associate Professor of Surgery, Harvard Medical School
1:45 pm PANEL ON BIOINFORMATICS, ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING FOR A MULTI- MODALITY DATA ANALYSIS FOR PRECISION DIAGNOSIS AND TREATMENT PLANNING
Moderators:
Paul Boutros, PhD, MBA
Arnold C Cinman, MD, FACS, Partner, Tower Urology; and Attending Urologist, Cedars-Sinai Medical Center, Los Angeles
Masoom Haider, MD
1:45 pm Personalization of Prostate Cancer Care through Integration of Data
Ilya Gipp, MD, PhD, Oncology Solutions Subject Matter Expert, Philips
1:57 pm Q & A
1:59 pm Radiological Perspective on the Emerging and Potential Role of Machine Learning
Masoom Haider, MD
2:11 pm Q & A
2:13 pm Radiomics and Pathomics of Prostate Cancer: Diagnosis, Prognosis and Predicting Treatment Response
Anant Madabhushi, PhD, FAIMBE, FIEEE, FNAI, Donnell Institute Professor and Director, Center for Computational Imaging & Personalized Diagnostics, Departments of Biomedical Engineering, Urology, Radiology, Pathology, Radiation Oncology, Electrical, Comp & Systems Engineering, Computer & Data Sciences and Gen Med Sciences, Case Western Reserve University (TBC)
2:25 pm Q & A
2:27 pm Artificial Intelligence
Liang Wang, MD, PhD, Professor, Attending Radiologist, Vice-Chairman for the Research and Development, Director of Urogenital Imaging, Department of Radiology, Beijing Friendship Hospital Capital Medical University, China
2:39 pm Q & A
2:41 pm Update on Multi-Factorial Nomograms
Amita Dave, PhD, Attending Physicist and Deputy Service Chief for Predictive Informatics, Director of Quantitative Imaging, Memorial Sloan Kettering Cancer Center
Andreas G. Wibmer, MD, Assistant Attending, Department of Radiology, Memorial Sloan Kettering Cancer Center
2:53 pm Q & A
2:55 pm – 3:20 pm Panel Discussion: Bioinformatics, Artificial Intelligence and Machine Learning
3:20 pm – 3:40 pm: Presentation of Winning Abstracts
3:40 pm – 5:30 pm SUMMARY PANEL DISCUSSION – SUMMIT HIGHLIGHTS
5:30 pm ADJOURN