SCIENTIFIC PROGRAM

Boston Marriot Long Wharf | August 3-5, 2018

Program at a Glance

Event Schedule Subject to Change

7:00 AM
EXHIBITS AND CONTINENTAL BREAKFAST

8:00 AM
WELCOME AND INTRODUCTION

8:10 AM – 12:30 PM
SESSION I. PRECISION SCREENING AND DIAGNOSTIC ASSESSMENT FOR EARLY DETECTION OF CLINICALLY SIGNIFICANT PROSTATE CANCER

12:30 PM – 1:30 PM
LUNCH BREAK

1:30 PM – 6:30 PM
SESSION II. DIAGNOSTIC ASSESSMENT OF MEN WITH PROVEN LOCALIZED PROSTATE CANCER: Prediction of Progression, Staging, Patient Selection for Treatment and Post-Operative Assessment

7:00 PM
DINNER RECEPTION 

 

7:30 PM
INDUSTRY LEADERSHIP SESSION ON ACCELERATING INNOVATION AND ADOPTION: 
Current Challenges and Solutions – Role of Technology Assessment, Clinical Guidelines and Reimbursement Policy

 

9:00 PM
POSTER SESSION

SUNDAY, AUGUST 5, 2018

7:00 AM – 8:00 AM
EXHIBITS AND CONTINENTAL BREAKFAST

8:00 AM – 9:30 AM
SESSION III: PRECISION DIAGNOSTICS AND EMERGING ROLE OF FOCAL TREATMENT

9:30 AM – 12:30 PM
SESSION IV: PRECISION ONCOLOGY FOR RECURRENT AND ADVANCED PROSTATE CANCER

 

12:30 PM – 1:30 PM
LUNCH BREAK

1:30 PM – 2:45 PM
SESSION V: SUMMARY PANEL DISCUSSION – 
Summit Highlights: Most Promising Current Clinical and Research Trends in Precision Screening, Diagnosis and Treatment and Expediting their Transfer from Laboratories to Patients

3:00 PM
BRAIN TRUST MEETING: 
Development of the Consensus Recommendations – Defining and Addressing Priority Needs in Precision Clinical Care by Designing Research, Medical Education and Training Programs 

5:30 PM
ADJOURN

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8:00 AM

WELCOME AND INTRODUCTION:

Faina Shtern, MD, President and CEO, AdMeTech Foundation

8:10 AM

SESSION I. PRECISION SCREENING AND DIAGNOSTIC ASSESSMENT FOR EARLY DETECTION OF CLINICALLY SIGNIFICANT PROSTATE CANCER

Moderators

andriole_350

Gerald Andriole, MD, Robert Royce Distinguished Professor, Chief of Urologic Surgery, and Vice-Chair, Department of Surgery, Washington University School of Medicine, Barnes-Jewish Hospital, and Member, National Comprehensive Cancer Network (NCCN)’s Prostate Cancer Early Detection Panel

Kibel, Adam MD

Richard Babayan, MD, Professor and Chairman, Department of Urology, Boston University School of Medicine; and Chief of Urology, Boston Medical Center

Blute-Michael

Michael Blute, MD, Walter S. Kerr, Jr. Professor of Urology and Surgery, Harvard Medical School; and Chief of Urology, Massachusetts General Hospital

8:15 AM
State of the Art in “Smart” Prostate Cancer Screening:
Defining the Need for Precision Diagnostics

Sigrid Carlsson, MD, PHD, MPH, Assistant Attending Epidemiologist, Department of Surgery (Urology Service), Memorial Sloan Kettering Cancer Center and Associate Professor of Experimental Urology, Sahlgrenska Academy, Gothenburg University, Sweden

8:30 AM
Q & A

Klein

8:35 AM
IsoPSA, a Novel Structure-Based Assay for Screening

Eric Klein, MD, Chairman, Glickman Urological and Kidney Institute, Cleveland Clinic

8:50 AM
Q & A

Crawford

8:55 AM

A Way Forward in Early Detection Of Prostate Cancer: Integrating Liquid Molecular Markers 

David Crawford, MD, E. David Crawford Distinguished Endowed Chair in Urology, University of Colorado, Denver

9:10 AM
Q & A

Michael_donovan

9:15 AM
Liquid Biopsy: Definition and Clinical Utility


Michael Donovan, MD, PhD, Professor of Pathology, Mount Sinai Medical Center

9:30 AM
Q & A

9:35 AM
Current and
Emerging Imaging Tools for Improving Risk Assessment, Selection of Patients for Biopsy and Tissue Sampling

Jeffrey C Weinreb 600x600
jelle-barentsz photo 600x600

9:35 AM
Multi-Parametric (mp) Magnetic Resonance Imaging and PI-RADS for Risk Assessment Prior to Biopsy

Jeffrey Weinreb, MD, Professor and Vice Chair for Strategic Planning and Innovation, Department of Diagnostic Radiology and Biomedical Imaging,Yale School of Medicine

9:50 AM
mpMRI, PI-RADS and Multi-Modality Image Fusion for Target Definition and Tissue Sampling

Jelle Barentsz, MD, PhD, Chair and Professor of Radiology Prostate MR Center of Excellence, Nijmegen Medical Center, Radboud University, The Netherlands

10:05 AM
Q & A

10:10 AM – 10:30 AM
Coffee Break

Sangeet-Ghai-600x600

10:30 AM
Real-time High Resolution Micro-Ultrasound for Targeted Biopsies – A Multi-Center Comparison to mpMRI

Sangeet Ghai, MD, Associate Professor, Department of Medical Imaging, University of Toronto, Canada

10:45 AM
Q & A

christopher-filson

10:50 AM
Effectiveness and Economic Implications of Population-Level Adoption of MRI-Guided Prostate Biopsies

Christopher Filson, MD, Assistant Professor of Urology, Emory University

Sprenkle-2

11:05 AM
NCCN Guidelines for Early Detection of Prostate Cancer

Preston Sprenkle, MD, Assistant Professor of Surgery, Yale University School of Medicine; and Member, NCCN Prostate Cancer Early Detection Panel

11:20 AM
Q & A

Punnen

11:25 AM
Integration of In Vitro Diagnostics with In Vivo Imaging

Sanoj Punnen, MD, Assistant Professor of Surgery, University of Miami Miller School of Medicine

Cooperberg
Moses_Kelvin_small
Kibel, Adam MD
Stephen-Zappala-2

11:40 AM
Panel: Emerging Best Practices in Precision Screening and Diagnostic Assessment for Early Detection of Prostate Cancer

Moderators, Speakers and

Matthew Cooperberg, MD, MPH, Associate Professor, Department of Urology and Epidemiology Biostatistics, Helen Diller Family Chair in Urology, University of California, San Francisco

Kelvin Moses, MD, PhD, Assistant Professor of Urology, Department of Urologic Surgery, Vanderbilt University Medical Center, Chief of Urology, Nashville General Hospital, and Member, Vanderbilt-Ingram Cancer Center; and Member, NCCN Prostate Cancer Early Detection Panel

Peter Pinto, MD, Head of Prostate Cancer Section, Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health

Stephen Zappala, MD, Assistant Clinical Professor of Urology, Tufts University School of Medicine

12:30 PM – 1:30 PM
Lunch Break

1:30 PM

SESSION II. DIAGNOSTIC ASSESSMENT OF MEN WITH PROVEN LOCALIZED PROSTATE CANCER:

Prediction of Progression, Staging, Patient Selection for Treatment and Post-Operative Assessment

Moderators

Crawford

David Crawford, MD, E. David Crawford Distinguished Endowed Chair in Urology, University of Colorado, Denver

Kibel, Adam MD

Angelo DeMarzo, MD, PhD, Associate Professor of Pathology, Urology, Oncology, Johns Hopkins University School of Medicine

Klein

Eric Klein, MD, Chairman, Glickman Urological and Kidney Institute, Cleveland Clinic

1:35 PM
In Vivo Imaging

Tempany

1:35 PM
Current Status of mpMRI and Multi-Modality Diagnostics – and Clinical Trial of the Eastern Cooperative Oncology Group and Amedical College of Radiology Imaging Network 

Clare Tempany, MD,

Ferenc Jolesz, MD Professor of Radiology, Harvard Medical School; Vice Chair, Research Radiology, Brigham and Women’s Hospital; and Director, National Center for Image-Guided Therapy

1:50 PM
Q&A

Haider 2

1:55 PM
Radiomics and Machine Learning with Multiparametric Imaging

Masoom Haider, MD, Professor of Radiology and Vice Chair, Radiomics and Quantitative Imaging, University of Toronto, Canada

2:10 PM
Q&A

rstoyanova-130x182

2:15 PM
Radiogenomics of Tumor Habitats – Addressing Prostate Cancer Heterogeneity:

Radka Stoyanova, PhD, Professor and Director, Imaging and Biomarkers Research, Department of Radiation Oncology and Associate Member, Sylvester Comprehensive Cancer Center, Miller School of Medicine University of Miami

2:30 PM
Q&A

2:35 PM
Tissue-Based
Pathologic Assessment, Genomics and Phenotypic Biomarkers

Thomas Wheeler-MD-v2

2:35 PM
Anatomic Pathology

Thomas Wheeler, MD, Chairman and Professor of Pathology, Baylor College of Medicine

Kibel, Adam MD

2:50 PM
Molecular Pathology

Angelo DeMarzo, MD, PhD, Associate Professor of Pathology, Urology, Oncology, Johns Hopkins University School of Medicine

3:05 PM
Q&A

Klein

3:10 PM
Genetic Cancer Profiling

Eric Klein, MD, Chairman, Glickman Urological and Kidney Institute, Cleveland Clinic

3:25 PM
Q&A

Albala2

3:30 PM
Phenotypic Biomarkers and Precision Oncology

David Albala, MD, Chief of Urology, Crouse Hospital in Syracuse, New York; and Medical Director for Associated Medical Professionals

jennifer-rider-photo

3:45 PM
Surrogate Outcomes

Jennifer Rider, ScD, MPH, Assistant Professor, Department of Epidemiology, Boston University School of Public Health

4:00 PM
Q&A

4:05 PM
Coffee Break

Cooperberg

4:25 PM
Emerging Trends in Prostate Cancer Care: Impact of Precision Diagnostics 

Matthew Cooperberg, MD, MPH

4:40 PM
Q&A

4:45 PM
Radiogenomics: Emerging and Future Impact on Treatment Selection and Monitoring 

Punnen

4:45 PM
Active Surveillance

Sanoj Punnen, MD

Kibel, Adam MD

5:00 PM
Focal Treatment

Peter Pinto, MD

feldman

5:15 PM
Immediate Standard Whole Gland Treatment: Radical Prostatectomy and EBRT

Adam Feldman, MD, MPH, Assistant Professor of Surgery and Director of Combined Harvard Urology Oncology Fellowship, Massachusetts General Hospital, Harvard Medical School

5:30 PM

Q&A

Sangeet-Ghai 600x600
Susan Noworolski 600x600
DSC_0031
Jacene
Dr_Daniel_Margolis
weber-wolfgang
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5:40 PM – 6:30 PM

Panel on Diagnostic Evaluation of Men with Proven Localized Prostate Cancer and its Impact on Treatment Selection and Monitoring

Speakers, Moderators and Panel Members –

  • Comments on Ultrasound and Multi-Modality Imaging – Sangeet Ghai, MD
  • Comments on Improved Diagnosis of Clinically Significant PC – Susan Noworolski, PhD, Associate Professor, Department of Radiology, UCSF
  • Comments on mpMRI for Cost-Effective Active Surveillance – Sejal Patel, MSc, Radboud University, The Netherlands
  • Comments on Molecular Imaging – Heather Jacene, MD, Assistant Professor of Radiology and Associate Program Director, Brigham and Women’s Joint Program in Nuclear Medicine, Harvard Medical School
  • Comments on Non-Invasive PSMA – Daniel Margolis, MD, Associate Professor of Radiology and Director, Prostate MRI and Abdominal Imaging, Weill Cornell Medicine
  • Comments on Intraoperative Molecular Imaging for Staging –  Wolfgang Weber, MD, Professor and Chair,Department of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Germany
  • Comments on Multi-Modality Novel Nomograms for Improved Risk Stratification – Amita Shukla-Dave, PhD, Deputy Service Chief for Predictive Informatics

7:00 pm

Dinner Reception

7:30 pm

Industry Leadership Session on Accelerating Innovation and Adoption:

Current Challenges and Solutions – Role of Technology Assessment, Clinical Guidelines and Reimbursement Policy

Moderators

richard_frank_MD-600x600

Richard Frank, MD, PhD, Chief Medical Officer, Siemens Healthineers

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Grannum R Sant, MD, FRCS, FACS, Professor and Former Chair of Urology, Tufts University School of Medicine; Former Head, Oncology/Urology Medical Affairs, Sanofi, and Rare Genetic Diseases, Genzyme

richard_frank_MD-600x600

7:30 PM

Introduction: Four Hurdles to Adoption of Innovations into Clinical Practice 

Richard Frank, MD, PhD

Heinrich-Von-Busch-1
Artem Boltyenkov

7:40 PM

mpMRI: Clinical Utilization and Health Economics

Heinrich von Busch, PhD, Product Owner, Artificial Intelligence for Oncology Imaging; and Artem Boltyenkov, PhD, Senior Manager, Global Health Economics and Outcomes Research, Siemens Healthineers

Jonathan-Allis
dr-bela-denes-photo

7:55 PM

PET/CT with Axumin (18F-fluciclovine): Clinical Implementation

Blue Earth Diagnostics: Jonathan Allis, PhD, CEO

Kibel, Adam MD

8:10 PM

PET PSMA: Emerging Broad-Based Clinical Utility

Steven Rowe, MD, PhD, Assistant Professor of Radiology, Johns Hopkins University School of Medicine

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8:15 PM

Improving Prostate Biopsy Guidance: Moving to 29 MHz Micro-Ultrasound

Brian Wodlinger, PhD, Manager, Advanced Development and Clinical Research, Exact Imaging

Moses_Kelvin_small

8:20 PM

In Vitro Diagnostics: Clinical Adoption

Kelvin Moses, MD, PhD

8:30 PM

Genomic Cancer Profiling: Clinical Role and Adoption

Brian Liu

8:30 PM

Perspectives from Myriad Genetics

Brian Liu, PhD, Medical Science Liaison-Urology, Myriad Geneitcs

8:35 PM

Perspective from Genomic Health 

Lisa Kaminsky, RN, BSN, CNOR, Sr. Medical Science Liaison

Antoine Leroy

8:40 PM

Targeted Biopsy and Focal Treatment: Emerging Clinical Role

Antoine Leroy, President, Koelis

Kibel, Adam MD
Jeffrey C Weinreb 600x600

8:45 PM

Panel Discussion: Recommendations for Action to Accelerate Adoption

Moderators, Speakers and Peter Pinto, MD and Jeffrey Weinreb, MD

richard_frank_MD-600x600
82811-profile-large

8:55 PM

Summary of Actions

Moderators: Richard Frank, MD, PhD and Grannum R. Sant, MD, FRCS, FACS

9:00 pm

Poster Session and Competition

8:00 AM

SESSION III: PRECISION DIAGNOSTICS AND EMERGING ROLE OF FOCAL TREATMENT

Moderators

Kibel, Adam MD

Peter Pinto, MD, Head of Prostate Cancer Section, Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health

Mitchell Sokoloff-MD

Mitchell Sokoloff, MD, Professor and Chair of Urology, University of Massachusetts School of Medicine

CLARE TEMPANY

Clare Tempany, MD, Ferenc Jolesz MD Professor of Radiology, Harvard Medical School and Vice Chair for Radiology Research, Brigham and Women’s Hospital

8:05 AM
Multimodality Precision Diagnostics for Target Definition

Srinivas-Vourganti-1

8:05 AM
MRI/Ultrasound Fusion

Srinivas Vourganti, MD, Urologic Oncologist, Department of Urology and Assistant Professor, Rush University Medical Center

Verma

8:15 AM
Multi-Modality Imaging

Sadhna Verma, MD, MD, FSAR, Professor of Radiology, Director, Prostate Imaging Program, University of Cincinnati Cancer Institute and the Veterans Administration Hospital

feller

8:25 AM
Radiogenomics

John Feller, MD, Founder, Desert Medical Imaging

8:35 AM
Q&A

8:40 AM
Overview of Patient Selection, Monitoring and Outcomes

Futterer

8:40 AM
Radiology Perspective

Jurgen Futterer, MD, PhD, Interventional Radiologist, Nijmegen Medical Center and Professor, University of Twente, The Netherlands

Rastinehad

8:55 AM
Urology Perspective: Clinical Trial Design and Gold Nanoparticle-Directed Focal Ablation

Art Rastinehad, DO, FACOS, Associate Professor of Urology and Radiology, and Director, Focal Therapy and Interventional Urology Program, Icahn School of Medicine at Mount Sinai Health System

9:10 AM
Panel Discussion:
Moderators and Speakers

9:30 AM

SESSION IV: PRECISION ONCOLOGY FOR RECURRENT AND ADVANCED PROSTATE CANCER

Moderators

Kibel, Adam MD

Angelo DeMarzo, MD, PhD, Associate Professor of Pathology, Urology, Oncology, Johns Hopkins University School of Medicine

Petrylac

Daniel Petrylak, MD, Professor of Medicine (Medical Oncology) and Urology; and Co-Director, Signal Transduction Research Program, Yale University Cancer Center

Petrylac

9:35 AM
Overview of Advanced Prostate Cancer, Including Oligometastatic Disease

Daniel Petrylak, MD

9:50 AM
Q&A

Nanus

9:55 AM
Liquid Biopsy

David Nanus, MD, Mark W. Pasmantier Professor and Chief, Hematology and Oncology, New York-Presbyterian, and Director of Genitourinary Oncology, Weill Cornell Medicine

10:10 AM
Q&A

Kibel, Adam MD

10:15 AM
Genomic Testing, including Germline Mutations 

 Angelo DeMarzo, MD, PhD

10:30 AM
Q&A

10:35 AM
Coffee Break

10:55 AM
Molecular and Multi-Modality Imaging

Jacene

10:55 AM
Overview

Heather Jacene, MD, Assistant Professor of Radiology and Associate Program Director, Brigham and Women’s Joint Program in Nuclear Medicine, Harvard Medical School

andriole_350

11:10 AM
LOCATE Trial – Impact of PET with 18F-fluciclovine on Management of Patients with Suspected Recurrence

Gerald L. Andriole, MD

11:25 AM
Q&A

Kibel, Adam MD

11:30 AM
PSMA PET: Steven Rowe, MD, PhD, Assistant Professor of Radiology, Johns Hopkins University School of Medicine

weber-wolfgang

11:45 AM
PSMA Based Theranostics of Prostate Cancer

Wolfgang Weber, MD

12:00 PM
Q&A

12:05 PM

Panel Discussion
Moderators and Speakers

12:30 PM – 1:30 PM
Lunch

1:30 PM

SESSION V: SUMMARY PANEL DISCUSSION

Session Leaders

Gerald Andriole, MD, Matthew Cooperberg, MD, MPH, David Crawford, MD, Angelo Demarzo, MD, PhD, Masoom Haider, MD, Eric Klein, MD, Daniel Petrylak, MD, Peter Pinto, MD, Faina Shtern, MD, Clare Tempany, MD, and Wolfgang Weber, MD

1:30 PM
SUMMIT HIGHLIGHTS: Most Promising Current Clinical and Research Trends in Precision Screening, Diagnosis and Treatment and Expediting their Transfer from Laboratories to Patients

2:30 PM – 3:00 PM
Coffee Break

3:00 PM
BRAIN TRUST MEETING: Development of the Consensus Recommendations – Defining and Addressing Priority Needs in Precision Clinical Care by Designing Research, Medical Education and Training Programs 

Discussion Leaders: Moderators, Speakers, Panelists

5:30 PM
ADJOURN