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ADMETECH'S RESEARCH PROGRAM

Introduction

AdMeTech Foundation’s research program has been instrumental for facilitating major breakthroughs in research and development of prostate cancer imaging and minimally-invasive treatment since its establishment in 1997. AdMeTech focuses on stimulating new ideas and producing ground-breaking results and/or new technologies of high impact on patient care, frequently within one year after grant awards (see specific examples below). The cornerstone of this program and its success is the design and implementation of the Brain Trust meetings. These meetings bring together multi-disciplinary leaders from medicine, industry, government agencies, and advocacy groups to achieve two major goals:

  1. To stimulate creation of new ideas and breakthrough research projects in the field of image-guided diagnosis and treatment of prostate cancer; and
  2. To encourage talented investigators to apply their knowledge and tools to the advancement of prostate cancer imaging. 

Consequently, Brain Trust enables AdMeTech Foundation to support early stages of the high-impact research projects, before other funding entities are prepared to take a risk. At that early stage, the investment is at its lowest and the impact is at its highest. The research accomplishments described below are direct results of the AdMeTech’s Brain Trust meetings and highlight their critical importance in the overall research program.

Grants 2003-2011

    DOD Grant # DAMD 17-03-2-0055
    Title: “Molecular Imaging for Prostate Cancer”
    Date of Funding: August 2003 through August 2010

    DOD Grant # W81XMH-09-1-0552
    Title: “Molecular Imaging for Prostate Cancer”
    Date of Funding: August 2009 through August 2011

Brain Trusts & Research Projects

Research Projects 2003 - 2005
In August 2001, AdMeTech Foundation, with support of the Prostate Cancer Foundation, had convened a meeting of the pioneers of molecular imaging with the leaders of prostate cancer research in the areas of medical oncology, urologic surgery, radiation medicine and pathology. As the result of this event, the field of molecular imaging of prostate cancer has been established and the following investigators and research projects have been developed and funded:.read more

Research Projects 2005 - 2008
The research conducted between 2005 and 2008 was the direct result of the Brain Trust meetings of February 2004, October 2005, March 2006, and early 2007 and continued to result in the development of novel, breakthrough imaging methods for early detection, accurate diagnosis, and minimally-invasive treatment of prostate cancer. These imaging methods are based largely on the in vivo visualization of novel molecular markers which have been shown by in vitro experiments to be specific to prostate cancer. Each team identified a novel imaging agent that made it possible to target prostate cancer-specific molecules. .read more

Research Projects 2008 - 2011
AdMeTech has had a series of Brain Trust Meetings in prostate MRI in 2007 and 2008, followed by the Consensus Conference in January 2009. As the result of these meetings, prostate MRI was identified as the most promising and mature experimental imaging tool for prostate cancer, and AdMeTech funded the International Prostate MRI Working Group. The goal of this research program is to develop and implement a short-and long-term research strategy and to expedite development and testing of prostate MRI, which has been shown in preliminary studies in the US and Europe to improve detection, staging and treatment of prostate cancer. This program supports critical, potentially breakthrough areas of research in MRI and molecular imaging conducted at the Harvard Medical School, University of Nijmegen in Holland, University of Chicago, Institute for Cancer Research and Royal Marsden Hospital in the United Kingdom, UCSF, Memorial Sloan Kettering Cancer Center, and other institutions. . read more

Publications, Abstracts, and Presentations (Selected):...read more

Strategic Planning

Continue to expand the organizational and administrative infrastructure of the AdMeTech’s Research Program, which integrates the key personnel, expertise, technologies, resources and environment of all the participating institutions to facilitate advancement of prostate MRI and molecular imaging in general. Jointly with the National Institutes of Health in January 2009, AdMeTech convened Consensus Conference which reviewed the current state of the art in prostate cancer care, identified critical clinical needs and developed future research strategy to address them. It was preceded by the meeting of the Organizing Committee in July 2008, which had framed the conference agenda and recommended faculty members.

Expected Outcomes

1) It is anticipated that a comprehensive research strategy for the field of prostate MRI will be created that will facilitate advancement, clinical testing and implementation of this technology;
2) It is anticipated that critical technical areas in prostate MRI will be advanced and pilot studies will be completed to demonstrate the value of prostate MRI in early detection and prediction of tumor response to radiation treatment;
3) It is anticipated that novel research strategy and novel research ideas will be developed for the high-priority research projects that would facilitate development and implementation of prostate imaging for improved prostate cancer care.

Summary

The research program led by AdMeTech represents a unique, integrated multi-institutional, multi-disciplinary effort which will expedite advancement of molecular imaging as the means to improve early diagnosis and treatment of prostate cancer. This program will address the following fundamental challenges in prostate cancer care:

1) Improved early detection and accurate diagnosis;
2) Guidance and monitoring of the individualized, minimally-invasive patient care;
3) Improved early assessment of response to treatment;
4) Integrated, strategic approach to research and development to expedite creation, evaluation and implementation of new and promising “cutting-edge” molecular imaging technologies.

 





IN THE HEADLINES
NATIONAL PROSTATE CANCER AWARENESS MONTH, 2012 PRESIDENT'S PROCLAMATION
  Proclamation
FOURTH ANNUAL MASSACHUSETTS STATE HOUSE PROSTATE CANCER AWARENESS DAY JUNE 28, 2012
  State House News Coverage
  Resolution of the Boston City Council
  Governor's Proclamation Recognizing June 28, 2012 as Prostate Cancer Awareness Day in the State of Massachusetts
  Resolutions of the Massachusetts General Court
  Program
  Event Sponsors
US SENATOR JOHN KERRY LEADS UNANIMOUS PASSAGE OF LEGISLATION IN US SENATE
  Press Release (June 14, 2012)
  Press Release (July 30, 2012)
  S. Res. 529
  Huffington Post
  Wall Street Journal
June 27,2012 Senator Boxer and Representative Cummings Introduce Historic Legislation to Promote Prostate Cancer Research
  Press Release
  Congressional Record
  Letter of support: from MA General Court to MA Delegation to US Congress
  Endorsing Organizations
  Senate Bill 3345
  House Resolution 6033
  Press Release of U.S. Senator Barbara Boxer
FATHERS DAY BRIEFING AND RECEPTION CONCERNING PROSTATE CANCER AND MEN'S HEALTH, BOSTON CITY COUNCIL, JUNE 13, 2012
  Program
INTERNATIONAL IMAGING EXPERTS COOPERATE TO ADVANCE PROSTATE CANCER CARE
  DotMed Press Coverage
  American College of Radiology Press Release
  AdMeTech Foundation Press Release
US Preventive Services Task Force (US PSTF) Recommends Against PSA Screening: Frames the Need to Recognize Prostate Cancer as a Public Health Priority & Issue a National Call to Action to Improve Diagnostic Tools for Early Detection
  AdMeTech Foundation Public Statement
  Key Statistics
SEPTEMBER 10TH, 2011 PCRI PRESENTS ADMETECHFOUNDATIONíS DANCE FOR A CURE OF PROSTATE CANCER
  Event Photos
  Boston Business Journal
  Flyer
  Registration
  Channel 22 News Coverage
June 27, 2012 Senator Boxer and Representative Cummings Introduce Historic Legislation to Promote Prostate Cancer Research
  Senate Bill 3345
  Press Release
  Congressional Record
  Letter of support: from MA General Court to MA Delegation to US Congress
Manogram Scores a Historic Victory in US Congress
  Press Release Original Legislation
Dancing with the Stars' Celebrity Hosts Dance for a Cure
  Press Release
  Event Flyer
FOURTH ANNUAL Massachusetts State House PROSTATE CANCER AWARENESS DAY June 28, 2012
  Program / RSVP
  Sponsor Levels
  Sponsor Registration Form
  Resolution of the Massachusetts General Court
February 2012 International Imaging Experts Cooperate to Advance Prostate Cancer Care
  DotMed Press Coverage
  American College of Radiology Press Release
  AdMeTech Foundation Press Release
Society of Nuclear Medicine Features AdMeTech
  Coverage
Arthur Murray Boston's 2012 Teach-a-Thon to Benefit AdMeTech Foundation's Dance for a Cure
  Event Flyer
  Media Alert
  Reuters:Arthur Murray Dance Studio of Boston Takes Steps to End the Prostate Cancer Crisis
Third Annual Prostate Cancer Awareness Day
  State House Prostate Cancer Awareness Day Photos
  Boston City Council Commends AdMeTech Foundation - September 14, 2011
  Poster Photos
  Flyer/Agenda
  RSVP to Attend
  RSVP for Poster
  Poster Requirements
  RSVP for Sponsor
  Sponsor Levels
AdMeTech Foundation Leads the Way in Creating Massachusetts Example of Making Prostate Cancer a Public Health Priority
  Watch NECN Coverage
  Massachusetts General Court Resolution
  Boston City Council Commendation
  Governor's Proclamation
  Press Release
  Reuters
US Preventive Services Task Force Recommends Against PSA Screening
  Draft
  Evidence
Third Annual Prostate Cancer Awareness Day at Massachusetts State House
  Reuters
  CBS
  NBC Coverage
  Media Alert
  Sponsors
President Obama Sets Historic Precedent: Proclamation of the National Prostate Cancer Awareness Month; Recognizes Imaging as a Key Research Area
  Official Statement
Celebrities, Leaders of Medicine Support AdMeTech and Dance for a Cure
  Video
Dancing with the Stars' Nick Kosovich Lends His Voice to Prosty the Spokesgland!
  Watch and share the video
MASSACHUSETTS PROSTATE CANCER COALITION'S ANNUAL EDUCATIONAL SYMPOSIUM - MAY 20, 2011
  Overview
  AdMeTech's Imaging Roundtable
ARTHUR MURRAY'S NATIONAL APPEAL TO SUPPORT ADMETECH'S DANCE FOR A CURE
  Announcement
  Reuters
  Press Coverage
  National Appeal
  Press Release
ADMETECH FOUNDATION JOINS EFFORT WITH PROSTATE CANCER RESEARCH INSTITUTE TO HOLD AN EDUCATIONAL IMAGING SEMINAR ON MARCH 27, 2011.
  Program
  Faculty Roster
  Press
ARTHUR MURRAY BOSTON'S TEACH-A-THON SUPPORTS DANCE FOR THE CURE - JANUARY 14, 2011
  More Info & RSVP
  Donate Now
  Press Coverage
BILL MORGANTI PRESENTS MARK BALLAS OF DANCING WITH THE STARS - JANUARY 15, 2011. PORTION OF PROCEEDS WILL BENEFIT DANCE FOR THE CURE
  More Info & RSVP
  Donate Now
  Press Coverage
  Photo
PRESTIGIOUS OHIO STAR BALL FEATURES ADMETECH FOUNDATIONíS DANCE FOR THE CURE OF PROSTATE CANCER. DANCING WITH THE STARS' CELEBRITY PRESENTED AWARDS.
  Press Release
  Pr Newswire
CELEBRITIES CHOREOGRAPH DANCE FOR THE CURE AT HOLLYWOOD DANCESPORT CHAMPIONSHIPS
  Press Release
  Reuters Coverage
  Photos
  WireImage Coverage
LEADERS OF MEDICINE AND ENTERTAINMENT LAUNCH DANCE FOR THE CURE AS A NATIONAL CAMPAIGN
  Press Release
  Photos
ABC TV MEGAHIT DANCING WITH THE STARS PRESENTS ADMETECH WITH 2 VIP TICKETS FOR THE GRAND FINALE
  Overview
  Purchase Raffle Tickets
NATIONAL CANCER INSTITUTE HIGHLIGHTS IMAGE-GUIDED, "SMARTER" PROSTATE CANCER CARE
  Press Release
ADMETECH ADDRESSES CONGRESSIONAL BLACK CAUCUS' (CBC) HEALTH BRAIN TRUST 2010
  Reuters Coverage
  Advocacy Supports PRIME Act
  Academy of Radiology, RSNA, AAPM and MITA Support PRIME Act
  Photos
NEW YORK TIMES EDITOR AND PROSTATE CANCER SURVIVOR DANA JENNINGS ON PATIENT CARE AND PERSONAL EXPERIENCE
  Book Review "Invasion of Prostate Snatchers"
  Personal Story - March 23, 2009
WHITE HOUSE PROCLAMATION--SEPTEMBER 2010 AS NATIONAL PROSTATE CANCER AWARENESS MONTH
  Presidential Proclamation
PRESTIGIOUS CAPITAL DANCESPORT FEATURES DANCE FOR THE CURE WORKSHOPS WITH SUPERSTARS, CHAMPIONSHIPS & SHOW
  Press Release
  Overview
  Dance Beat Article
  Photos
  Video
WIN A RAFFLE FOR A COMPETITIVE BALLGOWN BY DESIGNS TO SHINE OR EVENING DRESS BY ENTRADA COUTURE ($4000)
  Overview
  Purchase Raffle Tickets
ADMETECH COSPONSORS MEDICAL EXHIBIT IN US CONGRESS
  Letter from Chairman Towns
  Photos
ADMETECH HOSTS A SECOND PROSTATE CANCER AWARENESS DAY AT THE MASSACHUSETTS STATE HOUSE -
JUNE 16, 2010

  Media alert
  Governor's Proclamation
  Key legislators support PRIME Act
  State House Resolution
  Quotes
  Photos
ADMETECH CONVENES INTERNATIONAL LEADERS OF PROSTATE MRI -
MAY 6, 2010

  Consensus Statement
  Agenda
  Faculty Roster
  Press Release
  CNBC
PER ITS INVENTOR, PSA CAUSES "PUBLIC HEALTH DISASTER"
  New York Times Op-Ed
US CONGRESS HOLDS HISTORIC HEARING ON PROSTATE CANCER, ADMETECH TESTIFIES
  Press Release
  Hearing Announcement
  AdMeTech Testifies
  NBC Coverage
  USA TODAY
REP. CUMMINGS REINTRODUCES THE $650 MILLION PRIME ACT IN RESPONSE TO THE CONGRESSIONAL HEARING
  Press Coverage
  NBC Coverage
  PRIME Act H.R. 4756
AWARD WINNING IMAGING RESEARCH ADDRESSES THE FUNDAMENTAL CHALLENGE IN PROSTATE CANCER CARE AS FRAMED BY CONGRESSIONAL HEARING ON MARCH 4, 2010
  Press Coverage
  SCBT&MR Society Issues Lauterbur Award
US CONGRESS APPROVES $1.6 MILLION FOR ADMETECH'S RESEARCH PROGRAMS
  Coverage
SENATOR BOXER URGES US CONGRESS TO SUPPORT THE PROSTATE CANCER IMAGING AND MENíS EDUCATION (PRIME) ACT
  Congressional Record
  Letter to US Senate
  PRIME Act
CUMMINGS, WAXMAN AND OTHER MEMBERS OF US CONGRESS URGE NCI / NIH TO FUND PROSTATE IMAGING
  Letter
  Press Release
US CONGRESS PASSES HISTORIC RESOLUTION CALLING FOR INCREASED NATIONAL INVESTMENT IN PROSTATE CANCER IMAGING
  Press Release
  Resolution
  Coverage by Roll Call
June 12, 2008
  Rep. Elijah Cummings Successfully Introduces House Resolution 353 (Video)
  Democratic Leadership in US Congress supports Prostate Cancer Imaging (Video)
  Republican Leadership in US Congress supports Prostate Cancer Imaging (Video)
ADMETECH HOLDS PROSTATE CANCER AWARENESS DAY AT MASSACHUSETTS STATE HOUSE
  Program
  Press Release
  Coverage
  Photos
MASSACHUSETTS STATE HOUSE RECOGNIZES ADMETECH FOR PROSTATE CANCER AWARENESS DAY
  Resolution
BOSTON CITY COUNCIL RECOGNIZES ADMETECH FOR ITS ONGOING EFFORTS IN AWARENESS AND RESEARCH
  Resolution
  Photos
PRESIDENT OBAMA DECLARES SEPTEMBER, 2009 AS NATIONAL PROSTATE CANCER AWARENESS MONTH
  Press Release
WALL STREET JOURNAL COVERS PROSTATE CANCER IMAGING AND ITS ROLE IN:
  Accurate diagnosis - Part I
March 31, 2009
  Treatment - Part II
April 7, 2009
  Watchful waiting - Part III
April 17, 2009
NBC COVERS THE NEED TO CREATE LIFE-SAVING PROSTATE CANCER DIAGNOSTICS
  Coverage
FOX BUSINESS NEWS COVERS "THE MANOGRAM PROJECT" & THE NEED FOR NATIONAL INVESTMENT IN PROSTATE CANCER RESEARCH
  Coverage
ADMETECHíS CONSENSUS CONFERENCE OF JANUARY, 2009 BRINGS TOGETHER WORLD EXPERTS
  Agenda
  Faculty Members
  Consensus Statement
  Signed Letter to NIH and NCI
  Coverage by Reuters